Recent Publications


Conklin MW, Gangnon RE, …Friedl A, Keely P, Trentham-Dietz A. Collagen alignment as a predictor of recurrence after ductal carcinoma in situ. Cancer Epid. Biom. Prev. 2017 Nov 15. [Epub ahead of print]

Lee J, Jefcoate C. Monitoring of Dual CRISPR/Cas9-Mediated Steroidogenic Acute Regulatory Protein Gene Deletion and Cholesterol Accumulation Using High-Resolution Fluorescence In Situ Hybridization in a Single Cell. Front Endocrinol (Lausanne). 2017 Oct 25;8:289.

Ishihara S, Inman DR, Li WJ, Ponik SM, Keely PJ. Mechano-Signal Transduction in Mesenchymal Stem Cells Induces Prosaposin Secretion to Drive the Proliferation of Breast Cancer Cells. Cancer Res. 2017 77(22):6179-6189.

Ziegler TE, Sosa ME, Colman RJ. Fathering style influences health outcome in common marmoset (Callithrix jacchus) offspring. PLoS One. 2017 Sep 28;12(9):e0185695.

Mehta C, Johnson KD, … Bresnick EH. Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program. Cell Rep. 2017 Sep 19;20(12):2966-2979.

Maegawa S, Lu Y, Tahara T,… Colman RJ, Issa JJ. Caloric restriction delays age-related methylation drift. Nat Commun. 2017 Sep 14;8(1):539.

Rodriguez AM, Downs KM. Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula. Dev Biol. 2017 Dec 1;432(1):98-124.
Huang G, Massoudi D, Muir AM, …Greenspan DS. WBSCR16 Is a Guanine Nucleotide Exchange Factor Important for Mitochondrial Fusion. Cell Rep. 2017 Jul 25;20(4):923-934.

Park AC, Phan N, Massoudi D, …Greenspan DS. Deficits in Col5a2 Expression Result in Novel Skin and Adipose Abnormalities and Predisposition to Aortic Aneurysms and Dissections. Am J Pathol. 2017 Oct;187(10):2300-2311.

Chen B, Guo X, Tucholski T, Lin Z, McIlwain S, Ge Y. The Impact of Phosphorylation on Electron Capture Dissociation of Proteins: A Top-Down Perspective. J Am Soc Mass Spectrom. 2017 Jul 6.
Schneider A, Dhahbi JM, Atamna H, Clark JP, Colman RJ, Anderson RM. Caloric restriction impacts plasma microRNAs in rhesus monkeys. Aging Cell. 2017 Oct;16(5):1200-1203.

Maguire M, Bushkofsky JR, Larsen MC, … Jefcoate CR. Diet-dependent retinoid effects on liver gene expression include stellate and inflammation markers and parallel effects of the nuclear repressor Shp. J Nutr Biochem. 2017 Sep;47:63-74.

Lalit PA, Rodriguez AM, Downs KM, Kamp TJ. Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos. Nat Protoc. 2017 May;12(5):1029-1054.

Roy S, Sridharan R. Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes. Genome Res. 2017 Jul;27(7):1250-1262.

Cai W, Tucholski T, Chen B, Alpert AJ, McIlwain S, Kohmoto T, Jin S, Ge Y. Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy. Anal Chem. 2017 May 16;89(10):5467-5475.

Yamada Y, Kemnitz JW, Weindruch R, Anderson RM, Schoeller DA, Colman RJ. Caloric Restriction and Healthy Life Span: Frail Phenotype of Nonhuman Primates in the Wisconsin National Primate Research Center Caloric Restriction Study. J Gerontol A Biol Sci Med Sci. 2017 Apr 8..

Kensler RW, Craig R, Moss RL. Phosphorylation of cardiac myosin binding protein C releases myosin heads from the surface of cardiac thick filaments. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1355-E1364.

Wei L, Gregorich ZR, Lin Z, Cai W, … Moss RL, Diffee GM, Ge Y. Novel Sarcopenia-related Alterations in Sarcomeric Protein Post-translational Modifications in Skeletal Muscles Identified by Top-down Proteomics. Mol Cell Proteomics. 2017 Oct 18.

Huang G, Ge G, Izzi V, Greenspan DS. α3 Chains of type V collagen regulate breast tumour growth via glypican-1. Nat Commun. 2017 Jan 19;8:14351.

Mattison JA, Colman RJ, …Kemnitz JW, …, Weindruch R, de Cabo R, Anderson RM. Caloric restriction improves health and survival of rhesus monkeys. Nat Commun. 2017 Jan 17;8:14063.

Wang J, Massoudi D, …Greenspan DS, Feng JQ. BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis. J Dent Res. 2017 May;96(5):578-585.

Rodriguez AM, Jin DX, Wolfe AD, …Downs KM. Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula. Dev Biol. 2017 May 15;425(2):208-222.

Gregorich ZR, Cai W, Lin Z, Chen AJ, Peng Y, Kohmoto T, Ge Y. Distinct sequences and post-translational modifications in cardiac atrial and ventricular myosin light chains revealed by top-down mass spectrometry. J Mol Cell Cardiol. 2017 Jun;107:13-21.

Wang J,…Massoudi D, Greenspan DS, Feng JQ. Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation. J Endod. 2017 Jan;43(1):109-115.

Maguire M, Larsen MC, Foong YH, Tanumihardjo S, Jefcoate CR. Cyp1b1 deletion and retinol deficiency coordinately suppress mouse liver lipogenic genes and hepcidin expression during post-natal development. Mol Cell Endocrinol. 2017 Oct 15;454:50-68.

Jin Y, Wei L, Cai W, Lin Z, Wu Z, Peng Y, Kohmoto T, Moss RL, Ge Y. Complete Characterization of Cardiac Myosin Heavy Chain (223 kDa) Enabled by Size-Exclusion Chromatography and Middle-Down Mass Spectrometry. Anal Chem. 2017 May 2;89(9):4922-4930.

Burkard ME, Weaver BA. Tuning Chromosomal Instability to Optimize Tumor Fitness. Cancer Discov. 2017 Feb;7(2):134-136.
Lee J, Yamazaki T, Dong H, Jefcoate C. A single cell level measurement of StAR expression and activity in adrenal cells. Mol Cell Endocrinol. 2017 Feb 5;441:22-30. . Review.

Li M, …Saha K, Bhattacharyya A, Zhao X. Establishment of Reporter Lines for Detecting Fragile X Mental Retardation (FMR1) Gene Reactivation in Human Neural Cells. Stem Cells. 2017 Jan;35(1):158-169.

Wolfe AD, Rodriguez AM, Downs KM. STELLA collaborates in distinct mesendodermal cell subpopulations at the fetal-placental interface in the mouse gastrula. Dev Biol. 2017 May 1;425(1):44-57.

Hewitt KJ, Katsumura KR, Matson DR,…Bresnick EH. GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia. Dev Cell. 2017 Aug 7;42(3):213-225.e4.

Moss RL, Lynch TL 4th, Fitzsimons DP. Acting on an impulse (or two): Advantages of high-frequency tetanic onset in skeletal muscle. J Gen Physiol. 2017 Mar 6;149(3):297-300.

Zhang J, Chu LF, Hou Z, … Stewart R, Burlingham WJ, Murphy WL, Thomson JA. Functional characterization of human pluripotent stem cell-derived arterial endothelial cells. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30)

Massoudi D, Germer CJ, Glisch JM, Greenspan DS. Procollagen C-proteinase enhancer 1 (PCPE-1) functions as an anti-angiogenic factor and enhances epithelial recovery in injured cornea. Cell Tissue Res. 2017 Sep 21.

Jiang P, Hou Z, Bolin JM, Thomson JA, Stewart R. RNA-Seq of Human Neural Progenitor Cells Exposed to Lead (Pb) Reveals Transcriptome Dynamics, Splicing Alterations and Disease Risk Associations. Toxicol Sci. 2017 Sep 1;159(1):251-265.

Zhang J, Schwartz MP, Hou Z, …Thomson JA, Murphy WL. A Genome-wide Analysis of Human Pluripotent Stem Cell-Derived Endothelial Cells in 2D or 3D Culture. Stem Cell Reports. 2017 Apr 11;8(4):907-918.

Colman RJ. Non-human primates as a model for aging. Biochim Biophys Acta. 2017 Jul 17 Review.

Cervantes S, … Lee YS, Gomis R, Gasa R. Late-stage differentiation of embryonic pancreatic beta cells requires Jarid2. Sci Rep. 2017 Sep 14;7(1):11643.