Recent Publications

2020

Liu P, Soukup AA, Bresnick EH, Dewey CN, Keles S. PRAM: a novel pooling approach for discovering intergenic transcripts from large-scale RNA sequencing experiments. Genome Res. 2020 Sep 21:gr.252445.119. doi: 10.1101/gr.252445.119. Epub ahead of print. PubMed PMID: 32958497.

Kellie JF, Tran JC, Jian W, Jones B, Mehl JT, Ge Y, Henion J, Bateman KP. Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics, and Biotransformation in Preclinical and Clinical Studies: An Industry Perspective. J Am Soc Mass Spectrom. 2020 Sep 15. doi: 10.1021/jasms.0c00270. Epub ahead of print. PubMed PMID: 32869982.

Tucholski T, Ge Y. Fourier-transform ion cyclotron resonance mass spectrometry for characterizing proteoforms. Mass Spectrom Rev. 2020 Sep 7. doi: 10.1002/mas.21653. Epub ahead of print. PubMed PMID: 32894796.

Wu Z, Roberts DS, Melby JA, Wenger K, Wetzel M, Gu Y, Ramanathan SG, Bayne EF, Liu X, Sun R, Ong IM, McIlwain SJ, Ge Y. MASH Explorer: A Universal Software Environment for Top-Down Proteomics. J Proteome Res. 2020 Sep 4;19(9):3867-3876. doi: 10.1021/acs.jproteome.0c00469. Epub 2020 Aug 24. PubMed PMID: 32786689.

Thompson JD, Ou J, Lee N, Shin K, Cigliola V, Song L, Crawford GE, Kang J, Poss KD. Identification and requirements of enhancers that direct gene expression during zebrafish fin regeneration. Development. 2020 Jul 30;147(14):dev191262. doi: 10.1242/dev.191262. PubMed PMID: 32665240.

Jin N, Lera RF, Yan RE, Guo F, Oxendine K, Horner VL, Hu Y, Wan J, Mattison RJ, Weaver BA, Burkard ME. Chromosomal instability upregulates interferon in acute myeloid leukemia. Genes Chromosomes Cancer. 2020 Nov;59(11):627-638. doi: 10.1002/gcc.22880. Epub 2020 Jul 18. PubMed PMID: 32557940.

Liao R, Zheng Y, Liu X, Zhang Y, Seim G, Tanimura N, Wilson GM, Hematti P, Coon JJ, Fan J, Xu J, Keles S, Bresnick EH. Discovering How Heme Controls Genome Function Through Heme-omics. Cell Rep. 2020 Jun 30;31(13):107832. doi: 10.1016/j.celrep.2020.107832. PubMed PMID: 32610133; PMCID: PMC7382780.

You X, Chang YI, Kong G, Ranheim EA, Zhou Y, Johnson KD, Mehta C, Bresnick EH, Zhang J. Gata2 -77 enhancer regulates adult hematopoietic stem cell survival. Leukemia. 2020 Jun 27. doi: 10.1038/s41375-020-0942-6. Epub ahead of print. PubMed PMID: 32594099.

Fogg KC, Renner CM, Christian H, Walker A, Marty-Santos L, Khan A, Olson WR, Parent C, O’Shea A, Wellik DM, Weisman PS, Kreeger PK. Ovarian Cells Have Increased Proliferation in Response to Heparin-Binding Epidermal Growth Factor as Collagen Density Increases. Tissue Eng Part A. 2020 Jul;26(13-14):747-758. doi: 10.1089/ten.tea.2020.0001. Epub 2020 Jun 25. PubMed PMID: 32598229.

Adriansjach J, Baum ST, Lefkowitz EJ, Van Der Pol WJ, Buford TW, Colman RJ. Age-Related Differences in the Gut Microbiome of Rhesus Macaques. J Gerontol A Biol Sci Med Sci. 2020 Jun 18;75(7):1293-1298. doi: 10.1093/gerona/glaa048. PubMed PMID: 32052009.

Ash H, Ziegler TE, Colman RJ. Early learning in the common marmoset (Callithrix jacchus): Behavior in the family group is related to preadolescent cognitive performance. Am J Primatol. 2020 Aug;82(8):e23159. doi: 10.1002/ajp.23159. Epub 2020 Jun 9. PubMed PMID: 32515834.

Garcia PE, Adoumie M, Kim EC, Zhang Y, Scales MK, El-Tawil YS, Shaikh AZ, Wen HJ, Bednar F, Allen BL, Wellik DM, Crawford HC, Pasca di Magliano M. Differential Contribution of Pancreatic Fibroblast Subsets to the Pancreatic Cancer Stroma. Cell Mol Gastroenterol Hepatol. 2020;10(3):581-599. doi: 10.1016/j.jcmgh.2020.05.004. Epub 2020 May 23. PubMed PMID: 32454112.

Jiang P, Chamberlain CS, Vanderby R, Thomson JA, Stewart R. TimeMeter assesses temporal gene expression similarity and identifies differentially progressing genes. Nucleic Acids Res. 2020 May 21;48(9):e51. doi: 10.1093/nar/gkaa142. PubMed PMID: 32123905.

Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Mol Oncol. 2020 Aug;14(8):1898-1909. doi: 10.1002/1878-0261.12687. Epub 2020 May 19. PubMed PMID: 32255253; PMCID: PMC7400789.

Aon MA, Bernier M, Mitchell SJ, Di Germanio C, Mattison JA, Ehrlich MR, Colman RJ, Anderson RM, de Cabo R. Untangling Determinants of Enhanced Health and Lifespan through a Multi-omics Approach in Mice. Cell Metab. 2020 Jul 7;32(1):100-116.e4. doi: 10.1016/j.cmet.2020.04.018. Epub 2020 May 14. PubMed PMID: 32413334.

Bolus H, Crocker K, Boekhoff-Falk G, Chtarbanova S. Modeling Neurodegenerative Disorders in Drosophila melanogaster. Int J Mol Sci. 2020 Apr 26;21(9):3055. doi: 10.3390/ijms21093055. PubMed PMID: 32357532; PMCID: PMC7246467.

Goodroe AE, Fitz C, Power ML, Colman RJ, Capuano S 3rd, Ziegler TE. Evaluation of vitamin D3 metabolites in Callithrix jacchus (common marmoset). Am J Primatol. 2020 Jun;82(6):e23131. doi: 10.1002/ajp.23131. Epub 2020 Apr 9. PubMed PMID: 32270886

Singh A, Denu RA, Wolfe SK, Sperger JM, Schehr J, Witkowsky T, Esbona K, Chappell RJ, Weaver BA, Burkard ME, Lang JM. Centrosome amplification is a frequent event in circulating tumor cells from subjects with metastatic breast cancer. Mol Oncol. 2020 Apr 7;. doi: 10.1002/1878-0261.12687. [Epub ahead of print] PubMed PMID: 32255253.

Golenberg N, Squirrell JM, Bennin DA, Rindy J, Pistono PE, Eliceiri KW, Shelef MA, Kang J, Huttenlocher A. Citrullination regulates wound responses and tissue regeneration in zebrafish. J Cell Biol. 2020 Apr 6;219(4):e201908164. doi: 10.1083/jcb.201908164. PubMed PMID: 32328635; PMCID: PMC7147109.

Ray S, Chee L, Matson DR, Palermo NY, Bresnick EH, Hewitt KJ. Sterile α-motif domain requirement for cellular signaling and survival. J Biol Chem. 2020 May 15;295(20):7113-7125. doi: 10.1074/jbc.RA119.011895. Epub 2020 Apr 2. PMID: 32241909; PMCID: PMC7242717.

Lee H, Lee YS, Harenda Q, Pietrzak S, Oktay HZ, Schreiber S, Liao Y, Sonthalia S, Ciecko AE, Chen YG, Keles S, Sridharan R, Engin F. Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes. Cell Metab. 2020 Apr 7;31(4):822-836.e5. doi: 10.1016/j.cmet.2020.03.002. Epub 2020 Mar 26. PubMed PMID: 32220307; PMCID: PMC7346095.

Eshed-Eisenbach Y, Devaux J, Vainshtein A, Golani O, Lee SJ, Feinberg K, Sukhanov N, Greenspan DS, Susuki K, Rasband MN, Peles E. Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases. Neuron. 2020 Jun 3;106(5):806-815.e6. doi: 10.1016/j.neuron.2020.03.001. Epub 2020 Mar 24. PubMed PMID: 32209430.

Brown KA, Tucholski T, Eken C, Knott S, Zhu Y, Jin S, Ge Y. High-Throughput Proteomics Enabled by a Photocleavable Surfactant. Angew Chem Int Ed Engl. 2020 May 25;59(22):8406-8410. doi: 10.1002/anie.201915374. Epub 2020 Mar 24. PubMed PMID: 32097521

Haws SA, Yu D, Ye C, Wille CK, Nguyen LC, Krautkramer KA, Tomasiewicz JL, Yang SE, Miller BR, Liu WH, Igarashi K, Sridharan R, Tu BP, Cryns VL, Lamming DW, Denu JM. Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Mol Cell. 2020 Apr 16;78(2):210-223.e8. doi: 10.1016/j.molcel.2020.03.004. Epub 2020 Mar 23. PubMed PMID: 32208170; PMCID: PMC7191556.

Salamon RJ, Zhang Z, Mahmoud AI. Capturing the Cardiac Injury Response of Targeted Cell Populations via Cleared Heart Three-Dimensional Imaging. J Vis Exp. 2020 Mar 17;(157). doi: 10.3791/60482. PubMed PMID: 32250361.

Li M, Shin J, Risgaard R, Parries M, Wang J, Chasman D, Roy S*, Bhattacharyya A*, and Zhao X* (2020) Identification of FMR1 regulated molecular networks in human neurodevelopment, Genome Research 2020 Mar 16 (Online ahead of print). PubMed PMID: 32179589 DOI: 10.1101/gr.251405.119

Song JY, Pineault KM, Dones JM, Raines RT, Wellik DM. Hox genes maintain critical roles in the adult skeleton. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7296-7304. doi: 10.1073/pnas.1920860117. Epub 2020 Mar 13. PubMed PMID: 32170021; PMCID: PMC7132104.

Bhattacharyya A. Advancing Knowledge of Down Syndrome Brain Development and Function With Human Stem Cells. Am J Intellect Dev Disabil. 2020 Mar;125(2):90-92. doi: 10.1352/1944-7558-125.2.90. PubMed PMID: 32058817; PMCID: PMC7169307.

Adriansjach J, Baum ST, Lefkowitz EJ, Van Der Pol W, Buford TW, Colman RJ. Age-related differences in the gut microbiome of Rhesus macaques. J Gerontol Biol Sci. 2020 Feb 13. pii:glaa048. doi.org/10.1093/gerona/glaa048. [Epub ahead of print].

Zhang F, Wyche TP, Zhu Y, Braun DR, Yan JX, Chanana S, Ge Y, Guzei IA, Chevrette MG, Currie CR, Thomas MG, Rajski SR, Bugni TS. MS-Derived Isotopic Fine Structure Reveals Forazoline A as a Thioketone-Containing Marine-Derived Natural Product. Org Lett. 2020 Feb 21;22(4):1275-1279. doi: 10.1021/acs.orglett.9b04535. Epub 2020 Feb 4. PubMed PMID: 32017574; PMCID: PMC7494057.

Johnson JM, Hebert AS, Drane QH, Lera RF, Wan J, Weaver BA, Coon JJ, Burkard ME. A Genetic Toggle for Chemical Control of Individual Plk1 Substrates. Cell Chem Biol. 2020 Mar 19;27(3):350-362.e8. doi: 10.1016/j.chembiol.2020.01.007. Epub 2020 Feb 3. PubMed PMID: 32017920.

Rhoads TW, Clark JP, Gustafson GE, Miller KN, Conklin MW, DeMuth TM, Berres ME, Eliceiri KW, Vaughan LK, Duarte CW, Beasley TM, Colman RJ, Anderson RM. Molecular and functional networks linked to sarcopenia prevention by caloric restriction in rhesus monkeys. Cell Systems. 2020 Jan 22. pii: S2405-4712(19)30463-6. doi: 10.1016/j.cells.2019.12.002. [Epub ahead of print].

Dong Y, Xiong M, Chen Y, Tao Y, Li X, Bhattacharyya A, Zhang SC. Plasticity of Synaptic Transmission in Human Stem Cell-Derived Neural Networks. (2020) iScience. 2020 Jan 9;23(2):100829. doi: 10.1016/j.isci.2020.100829. [Epub ahead of print]. PMID:31981924

2019

Brok-Volchanskaya V.S., Bennin D. A., Suknuntha K, Klemm L. C., Huttenlocher A., Slukvin I. Effective and rapid generation of functional neutrophils from induced pluripotent stem cells using ETV2 modified mRNA. Stem Cell Reports. 2019 Dec 10;13(6):1099-1110.

Tran KA, Dillingham CM, Sridharan R. Coordinated removal of repressive epigenetic modifications during induced reversal of cell identity. EMBO J. 2019 Nov 15;38(22):e101681. doi: 10.15252/embj.2019101681. Epub 2019 Oct 4. PubMed PMID: 31583744; PubMed Central PMCID: PMC6856600.

Denomy C, Germain S, Haave B, Vizeacoumar FS, Freywald A, Weaver BA, Vizeacoumar FJ. Banding Together: A Systematic Comparison of The Cancer Genome Atlas and the Mitelman Databases. Cancer Res. 2019 Oct 15;79(20):5181-5190. doi: 10.1158/0008-5472.CAN-19-0585. Epub 2019 Aug 15. PubMed PMID: 31416843.

Pineault KM, Song JY, Kozloff KM, Lucas D, Wellik DM., “Hox11 expressing regional skeletal stem cells are progenitors for osteoblasts, chondrocytes and adipocytes throughout life” , Nat Commun. 2019 Jul 18;10(1):3168. doi: 10.1038/s41467-019-11100-4.

Berger AJ, Renner CM, Hale I, Yang X, Ponik SM, Weisman PS, Masters KS, Kreeger PK. Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling. Matrix Biol. 2020 Jan;85-86:80-93. doi: 10.1016/j.matbio.2019.07.006. Epub 2019 Jul 16. PubMed PMID: 31323325; PubMed Central PMCID: PMC6962577.

Brandt EB, Bashar SJ, Mahmoud AI. Stimulating ideas for heart regeneration: the future of nerve-directed heart therapy. Bioelectron Med. 2019;5:8. doi: 10.1186/s42234-019-0024-0. eCollection 2019. Review. PubMed PMID: 32232098; PubMed Central PMCID: PMC7098228.

Fogg KC, Olson WR, Miller JN, Khan A, Renner C, Hale I, Weisman PS, Kreeger PK. Alternatively activated macrophage-derived secretome stimulates ovarian cancer spheroid spreading through a JAK2/STAT3 pathway. Cancer Lett. 2019 Aug 28;458:92-101. doi: 10.1016/j.canlet.2019.05.029. Epub 2019 May 24. PubMed PMID: 31129149; PubMed Central PMCID: PMC6659112.

Tran KA, Pietrzak SJ, Zaidan NZ, Siahpirani AF, McCalla SG, Zhou AS, Iyer G, Roy S, Sridharan R. Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency. Cell Rep. 2019 May 7;27(6):1726-1741.e5. doi: 10.1016/j.celrep.2019.04.056. PubMed PMID: 31067459; PubMed Central PMCID: PMC6555151.

Kraynak M, Colman RJ, Flowers MT, Abbott DH, Levine JE. Ovarian estradiol supports sexual behavior but not energy homeostasis in female marmoset monkeys. Int J Obes (Lond). 2019 May;43(5):1034-1045. doi: 10.1038/s41366-018-0156-4. Epub 2018 Jul 18. PubMed PMID: 30022054.

Ren J, Zhou T, Pilli VSS, Phan N, Wang Q, Gupta K, Liu Z, Sheibani N, Liu B. Novel Paracrine Functions of Smooth Muscle Cells in Supporting Endothelial Regeneration Following Arterial Injury. Circ Res. 2019 Apr 12;124(8):1253-1265. doi: 10.1161/CIRCRESAHA.118.314567. PubMed PMID: 30739581; PubMed Central PMCID: PMC6459708.

Rodriguez AM, Kang J. Regeneration enhancers: Starting a journey to unravel regulatory events in tissue regeneration. Semin Cell Dev Biol. 2020 Jan;97:47-54. doi: 10.1016/j.semcdb.2019.04.003. Epub 2019 Apr 8. Review. PubMed PMID: 30953740; PubMed Central PMCID: PMC6783330.

Xu S, Wang G, Peng W, Xu Y, Zhang Y, Ge Y, Jing Y, Gong Z. Corosolic acid isolated from Eriobotrya japonica leaves reduces glucose level in human hepatocellular carcinoma cells, zebrafish and rats. Sci Rep. 2019 Mar 13;9(1):4388. doi: 10.1038/s41598-019-40934-7. PubMed PMID: 30867526.

Pfaltzgraff ER, Apfelbaum A, Kassa AP, Song JY, Jiang W, Suhan TK, Wellik DM, Lawlor ER. Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation. Cancers (Basel). 2019 Mar 6;11(3). pii: E313. doi: 10.3390/cancers11030313. PubMed PMID: 30845695.

Zhou T, Wang Q, Phan N, Ren J, Yang H, Feldman CC, Feltenberger JB, Ye Z, Wildman SA, Tang W, Liu B. Identification of a novel class of RIP1/RIP3 dual inhibitors that impede cell death and inflammation in mouse abdominal aortic aneurysm models. Cell Death Dis. 2019 Mar 6;10(3):226. doi: 10.1038/s41419-019-1468-6. PubMed PMID: 30842407; PubMed Central PMCID: PMC6403222.

Jin Y, Diffee GM, Colman RJ, Anderson RM, Ge Y. Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle. J Am Soc Mass Spectrom. 2019 Mar 4. doi: 10.1007/s13361-019-02139-0. [Epub ahead of print] PubMed PMID: 30834509.

Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11. PubMed PMID: 30742117.

Magli A, Baik J, Mills LJ, Kwak IY, Dillon BS, Mondragon Gonzalez R, Stafford DA, Swanson SA, Stewart R, Thomson JA, Garry DJ, Dynlacht BD, Perlingeiro RCR. Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm. PLoS Biol. 2019 Feb 26;17(2):e3000153. doi: 10.1371/journal.pbio.3000153. eCollection 2019 Feb. PubMed PMID: 30807574; PubMed Central PMCID: PMC6390996.

Tucholski T, Knott SJ, Chen B, Pistono P, Lin Z, Ge Y. A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Anal Chem. 2019 Feb 25. doi: 10.1021/acs.analchem.8b04082. [Epub ahead of print] PubMed PMID: 30758949.

Hall PE, Lewis R, Syed N, Shaffer R, Evanson J, Ellis S, Williams M, Feng X, Johnston A, Thomson JA, Harris FP, Jena R, Matys T, Jefferies S, Smith K, Wu BW, Bomalaski JS, Crook T, O’Neill K, Paraskevopoulos D, Khadeir RS, Sheaff M, Pacey S, Plowman PN, Szlosarek PW. A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma. Clin Cancer Res. 2019 Feb 22. doi: 10.1158/1078-0432.CCR-18-3729. [Epub ahead of print] PubMed PMID: 30796035.

Incitti T, Magli A, Darabi R, Yuan C, Lin K, Arpke RW, Azzag K, Yamamoto A, Stewart R, Thomson JA, Kyba M, Perlingeiro RCR. Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment. Proc Natl Acad Sci U S A. 2019 Feb 13. pii: 201808303. doi: 10.1073/pnas.1808303116. [Epub ahead of print] PubMed PMID: 30760602.

Soukup AA, Zheng Y, Mehta C, Wu J, Liu P, Cao M, Hofmann I, Zhou Y, Zhang J, Johnson KD, Choi K, Keles S, Bresnick EH. Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019 Mar 1;129(3):1180-1192. doi: 10.1172/JCI122694. Epub 2019 Feb 11. PubMed PMID: 30620726; PubMed Central PMCID: PMC6391105.

Dansereau G, Wey TW, Legault V, Brunet MA, Kemnitz JW, Ferrucci L, Cohen AA. Conservation of physiological dysregulation signatures of aging across primates. Aging Cell. 2019 Apr;18(2):e12925. doi: 10.1111/acel.12925. Epub 2019 Feb 11. PubMed PMID: 30746836.

Liang Y, Jin Y, Wu Z, Tucholski T, Brown KA, Zhang L, Zhang Y, Ge Y. Bridged Hybrid Monolithic Column Coupled to High-Resolution Mass Spectrometry for Top-Down Proteomics. Anal Chem. 2019 Feb 5;91(3):1743-1747. doi: 10.1021/acs.analchem.8b05817. Epub 2019 Jan 28. PubMed PMID: 30668094.

Churpek JE, Bresnick EH. Transcription factor mutations as a cause of familial myeloid neoplasms. J Clin Invest. 2019 Feb 1;129(2):476-488. doi: 10.1172/JCI120854. Epub 2019 Feb 1. Review. PubMed PMID: 30707109; PubMed Central PMCID: PMC6355228.

Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT Jr, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 Mar;35:101401. doi: 10.1016/j.scr.2019.101401. Epub 2019 Feb 1. PubMed PMID: 30738321.

Saltzman W, Abbott DH, Binkley N, Colman RJ. Maintenance of bone mass despite estrogen depletion in female common marmoset monkeys (Callithrix jacchus). Am J Primatol. 2019 Feb;81(2):e22905. doi: 10.1002/ajp.22905. Epub 2018 Aug 14. PubMed PMID: 30106167.

Kong F, Yamaoka Y, Ohama T, Lee Y, Li-Beisson Y. Molecular Genetic Tools and Emerging Synthetic Biology Strategies to Increase Cellular Oil Content in Chlamydomonas reinhardtii. Plant Cell Physiol. 2019 Jan 31. doi: 10.1093/pcp/pcz022. [Epub ahead of print] PubMed PMID: 30715500.

Cho E, Kang H, Kang DK, Lee Y. Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice. J Biol Chem. 2019 Mar 29;294(13):4981-4996. doi: 10.1074/jbc.RA118.005634. Epub 2019 Jan 30. PubMed PMID: 30700554; PubMed Central PMCID: PMC6442036.

Tang TWH, Chen HC, Chen CY, Yen CYT, Lin CJ, Prajnamitra RP, Chen LL, Ruan SC, Lin JH, Lin PJ, Lu HH, Kuo CW, Chang CM, Hall AD, Vivas EI, Shui JW, Chen P, Hacker TA, Rey FE, Kamp TJ, Hsieh PCH. Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair. Circulation. 2019 Jan 29;139(5):647-659. doi: 10.1161/CIRCULATIONAHA.118.035235. PubMed PMID: 30586712.

Mi HY, Jing X, Li ZT, Lin YJ, Thomson JA, Turng LS. Fabrication and modification of wavy multicomponent vascular grafts with biomimetic mechanical properties, antithrombogenicity, and enhanced endothelial cell affinity. J Biomed Mater Res B Appl Biomater. 2019 Jan 28. doi: 10.1002/jbm.b.34333. [Epub ahead of print] PubMed PMID: 30689292.

Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Vezina CM. Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds. Dev Biol. 2019 Jan 16. pii: S0012-1606(18)30719-X. doi: 10.1016/j.ydbio.2019.01.011. [Epub ahead of print] PubMed PMID: 30659795.

Cox BL, Erickson-Bhatt S, Szulczewski JM, Squirrell JM, Ludwig KD, Macdonald EB, Swader R, Ponik SM, Eliceiri KW, Fain SB. A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures. Magn Reson Med. 2019 May;81(5):3379-3391. doi: 10.1002/mrm.27644. Epub 2019 Jan 16. PubMed PMID: 30652350.

Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y. Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium. J Gen Physiol. 2019 Jan 14. pii: jgp.201812214. doi: 10.1085/jgp.201812214. [Epub ahead of print] PubMed PMID: 30642915.

Song JY, Pineault KM, Wellik DM. Development, repair, and regeneration of the limb musculoskeletal system. Curr Top Dev Biol. 2019;132:451-486. doi: 10.1016/bs.ctdb.2018.12.011. Epub 2019 Jan 11. PubMed PMID: 30797517.

Ge Y, Schuster MB, Pundhir S, Rapin N, Bagger FO, Sidiropoulos N, Hashem N, Porse BT. The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Nat Commun. 2019 Jan 11;10(1):172. doi: 10.1038/s41467-018-08076-y. PubMed PMID: 30635567; PubMed Central PMCID: PMC6329799.

Lee JJ, Cheng SJ, Huang CY, Chen CY, Feng L, Hwang DY, Kamp TJ, Chen HC, Hsieh PCH. Primary cardiac manifestation of autosomal dominant polycystic kidney disease revealed by patient induced pluripotent stem cell-derived cardiomyocytes.EBioMedicine. 2019 Feb;40:675-684. doi: 10.1016/j.ebiom.2019.01.011. Epub 2019 Jan 11. PubMed PMID: 30639418.

Giles J, Patel JR, Miller A, Iverson E, Fitzsimons D, Moss RL. Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C. J Gen Physiol. 2019 Jan 7;151(1):77-89. doi: 10.1085/jgp.201812238. Epub 2018 Dec 20. PubMed PMID: 30573635; PubMed Central PMCID: PMC6314388.

Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, Kamp TJ, Ye L, Hu S, Ogle BM, Rogers JM, Abel ED, Davis ME, Prabhu SD, Liao R, Pu WT, Wang Y, Ping P, Bursac N, Vunjak-Novakovic G, Wu JC, Bolli R, Menasché P, Zhang J. Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circ Res. 2019 Jan 4;124(1):161-169. doi: 10.1161/CIRCRESAHA.118.314216. PubMed PMID: 30605412; PubMed Central PMCID: PMC6350935.

Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8. PubMed PMID: 30604771; PubMed Central PMCID: PMC6318289.

Yin Y, Petersen AJ, Soref C, Richards WD, Ludwig T, Taapken S, Berndt E, Zhang SC, Bhattacharyya A.*(2019) Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds. Stem Cell Res. 2019 Jan;34:101365. doi: 10.1016/j.scr.2018.101365. Epub 2018 Dec 20. PubMed PMID: 30605841.