Recent Publications


Xu S, Wang G, Peng W, Xu Y, Zhang Y, Ge Y, Jing Y, Gong Z. Corosolic acid isolated from Eriobotrya japonica leaves reduces glucose level in human hepatocellular carcinoma cells, zebrafish and rats. Sci Rep. 2019 Mar 13;9(1):4388. doi: 10.1038/s41598-019-40934-7. PubMed PMID: 30867526.

Pfaltzgraff ER, Apfelbaum A, Kassa AP, Song JY, Jiang W, Suhan TK, Wellik DM, Lawlor ER. Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation. Cancers (Basel). 2019 Mar 6;11(3). pii: E313. doi: 10.3390/cancers11030313. PubMed PMID: 30845695.

Jin Y, Diffee GM, Colman RJ, Anderson RM, Ge Y. Top-down Mass Spectrometry of Sarcomeric Protein Post-translational Modifications from Non-human Primate Skeletal Muscle. J Am Soc Mass Spectrom. 2019 Mar 4. doi: 10.1007/s13361-019-02139-0. [Epub ahead of print] PubMed PMID: 30834509.

Shen M, Wang F, Li M, Sah N, Stockton ME, Tidei JJ, Gao Y, Korabelnikov T, Kannan S, Vevea JD, Chapman ER, Bhattacharyya A, van Praag H, Zhao X. Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice. Nat Neurosci. 2019 Mar;22(3):386-400. doi: 10.1038/s41593-019-0338-y. Epub 2019 Feb 11. PubMed PMID: 30742117.

Magli A, Baik J, Mills LJ, Kwak IY, Dillon BS, Mondragon Gonzalez R, Stafford DA, Swanson SA, Stewart R, Thomson JA, Garry DJ, Dynlacht BD, Perlingeiro RCR. Time-dependent Pax3-mediated chromatin remodeling and cooperation with Six4 and Tead2 specify the skeletal myogenic lineage in developing mesoderm. PLoS Biol. 2019 Feb 26;17(2):e3000153. doi: 10.1371/journal.pbio.3000153. eCollection 2019 Feb. PubMed PMID: 30807574; PubMed Central PMCID: PMC6390996.

Tucholski T, Knott SJ, Chen B, Pistono P, Lin Z, Ge Y. A Top-Down Proteomics Platform Coupling Serial Size Exclusion Chromatography and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry. Anal Chem. 2019 Feb 25. doi: 10.1021/acs.analchem.8b04082. [Epub ahead of print] PubMed PMID: 30758949.

Hall PE, Lewis R, Syed N, Shaffer R, Evanson J, Ellis S, Williams M, Feng X, Johnston A, Thomson JA, Harris FP, Jena R, Matys T, Jefferies S, Smith K, Wu BW, Bomalaski JS, Crook T, O’Neill K, Paraskevopoulos D, Khadeir RS, Sheaff M, Pacey S, Plowman PN, Szlosarek PW. A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma. Clin Cancer Res. 2019 Feb 22. doi: 10.1158/1078-0432.CCR-18-3729. [Epub ahead of print] PubMed PMID: 30796035.

Incitti T, Magli A, Darabi R, Yuan C, Lin K, Arpke RW, Azzag K, Yamamoto A, Stewart R, Thomson JA, Kyba M, Perlingeiro RCR. Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment. Proc Natl Acad Sci U S A. 2019 Feb 13. pii: 201808303. doi: 10.1073/pnas.1808303116. [Epub ahead of print] PubMed PMID: 30760602.

Soukup AA, Zheng Y, Mehta C, Wu J, Liu P, Cao M, Hofmann I, Zhou Y, Zhang J, Johnson KD, Choi K, Keles S, Bresnick EH. Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019 Mar 1;129(3):1180-1192. doi: 10.1172/JCI122694. Epub 2019 Feb 11. PubMed PMID: 30620726; PubMed Central PMCID: PMC6391105.

Dansereau G, Wey TW, Legault V, Brunet MA, Kemnitz JW, Ferrucci L, Cohen AA. Conservation of physiological dysregulation signatures of aging across primates. Aging Cell. 2019 Apr;18(2):e12925. doi: 10.1111/acel.12925. Epub 2019 Feb 11. PubMed PMID: 30746836.

Liang Y, Jin Y, Wu Z, Tucholski T, Brown KA, Zhang L, Zhang Y, Ge Y. Bridged Hybrid Monolithic Column Coupled to High-Resolution Mass Spectrometry for Top-Down Proteomics. Anal Chem. 2019 Feb 5;91(3):1743-1747. doi: 10.1021/acs.analchem.8b05817. Epub 2019 Jan 28. PubMed PMID: 30668094.

Churpek JE, Bresnick EH. Transcription factor mutations as a cause of familial myeloid neoplasms. J Clin Invest. 2019 Feb 1;129(2):476-488. doi: 10.1172/JCI120854. Epub 2019 Feb 1. Review. PubMed PMID: 30707109; PubMed Central PMCID: PMC6355228.

Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT Jr, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019 Mar;35:101401. doi: 10.1016/j.scr.2019.101401. Epub 2019 Feb 1. PubMed PMID: 30738321.

Kong F, Yamaoka Y, Ohama T, Lee Y, Li-Beisson Y. Molecular Genetic Tools and Emerging Synthetic Biology Strategies to Increase Cellular Oil Content in Chlamydomonas reinhardtii. Plant Cell Physiol. 2019 Jan 31. doi: 10.1093/pcp/pcz022. [Epub ahead of print] PubMed PMID: 30715500.

Tang TWH, Chen HC, Chen CY, Yen CYT, Lin CJ, Prajnamitra RP, Chen LL, Ruan SC, Lin JH, Lin PJ, Lu HH, Kuo CW, Chang CM, Hall AD, Vivas EI, Shui JW, Chen P, Hacker TA, Rey FE, Kamp TJ, Hsieh PCH. Loss of Gut Microbiota Alters Immune System Composition and Cripples Postinfarction Cardiac Repair. Circulation. 2019 Jan 29;139(5):647-659. doi: 10.1161/CIRCULATIONAHA.118.035235. PubMed PMID: 30586712.

Mi HY, Jing X, Li ZT, Lin YJ, Thomson JA, Turng LS. Fabrication and modification of wavy multicomponent vascular grafts with biomimetic mechanical properties, antithrombogenicity, and enhanced endothelial cell affinity. J Biomed Mater Res B Appl Biomater. 2019 Jan 28. doi: 10.1002/jbm.b.34333. [Epub ahead of print] PubMed PMID: 30689292.

Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Vezina CM. Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds. Dev Biol. 2019 Jan 16. pii: S0012-1606(18)30719-X. doi: 10.1016/j.ydbio.2019.01.011. [Epub ahead of print] PubMed PMID: 30659795.

Cox BL, Erickson-Bhatt S, Szulczewski JM, Squirrell JM, Ludwig KD, Macdonald EB, Swader R, Ponik SM, Eliceiri KW, Fain SB. A novel bioreactor for combined magnetic resonance spectroscopy and optical imaging of metabolism in 3D cell cultures. Magn Reson Med. 2019 May;81(5):3379-3391. doi: 10.1002/mrm.27644. Epub 2019 Jan 16. PubMed PMID: 30652350.

Gregorich ZR, Patel JR, Cai W, Lin Z, Heurer R, Fitzsimons DP, Moss RL, Ge Y. Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium. J Gen Physiol. 2019 Jan 14. pii: jgp.201812214. doi: 10.1085/jgp.201812214. [Epub ahead of print] PubMed PMID: 30642915.

Song JY, Pineault KM, Wellik DM. Development, repair, and regeneration of the limb musculoskeletal system. Curr Top Dev Biol. 2019;132:451-486. doi: 10.1016/bs.ctdb.2018.12.011. Epub 2019 Jan 11. PubMed PMID: 30797517.

Ge Y, Schuster MB, Pundhir S, Rapin N, Bagger FO, Sidiropoulos N, Hashem N, Porse BT. The splicing factor RBM25 controls MYC activity in acute myeloid leukemia. Nat Commun. 2019 Jan 11;10(1):172. doi: 10.1038/s41467-018-08076-y. PubMed PMID: 30635567; PubMed Central PMCID: PMC6329799.

Lee JJ, Cheng SJ, Huang CY, Chen CY, Feng L, Hwang DY, Kamp TJ, Chen HC, Hsieh PCH. Primary cardiac manifestation of autosomal dominant polycystic kidney disease revealed by patient induced pluripotent stem cell-derived cardiomyocytes.EBioMedicine. 2019 Feb;40:675-684. doi: 10.1016/j.ebiom.2019.01.011. Epub 2019 Jan 11. PubMed PMID: 30639418.

Giles J, Patel JR, Miller A, Iverson E, Fitzsimons D, Moss RL. Recovery of left ventricular function following in vivo reexpression of cardiac myosin binding protein C. J Gen Physiol. 2019 Jan 7;151(1):77-89. doi: 10.1085/jgp.201812238. Epub 2018 Dec 20. PubMed PMID: 30573635; PubMed Central PMCID: PMC6314388.

Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, Kamp TJ, Ye L, Hu S, Ogle BM, Rogers JM, Abel ED, Davis ME, Prabhu SD, Liao R, Pu WT, Wang Y, Ping P, Bursac N, Vunjak-Novakovic G, Wu JC, Bolli R, Menasché P, Zhang J. Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circ Res. 2019 Jan 4;124(1):161-169. doi: 10.1161/CIRCRESAHA.118.314216. PubMed PMID: 30605412; PubMed Central PMCID: PMC6350935.

Sun J, Carlson-Stevermer J, Das U, Shen M, Delenclos M, Snead AM, Koo SY, Wang L, Qiao D, Loi J, Petersen AJ, Stockton M, Bhattacharyya A, Jones MV, Zhao X, McLean PJ, Sproul AA, Saha K, Roy S. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019 Jan 3;10(1):53. doi: 10.1038/s41467-018-07971-8. PubMed PMID: 30604771; PubMed Central PMCID: PMC6318289.